-
Caspot ( Dorzolamide + Timolol
)
O General Information and Indications:
The combination of dorzolamide and
timolol is used to treat eye conditions, including glaucoma and ocular
hypertension, in which increased pressure can lead to a gradual loss of
vision. Dorzolamide and timolol is used for patients whose eye condition has
not responded to another medication. Dorzolamide is in a class of
medications called topical carbonic anhydrase inhibitors. Timolol is in a
class of medications called topical beta blockers. Dorzolamide and timolol
lowers pressure in the eye by decreasing the production of natural fluids in
the eye.
O Information For Users:
The combination of dorzolamide and timolol comes as an
eyedrop to apply to the eye. It is usually applied to the affected eye(s)
twice a day. To help you remember to use dorzolamide and timolol, use it
around the same time every day. Follow the directions on your prescription
label, ask your doctor or pharmacist If you have any questions. Use
dorzolamide and timolol exactly as directed. Do not use more or less of it
or use it more often than prescribed by your doctor.
Dorzolamide and timolol controls glaucoma and ocular hypertension but does
not cure them. Continue to use dorzolamide and timolol even if you feel
well. Do not stop using dorzolamide and timolol without informing your
doctor.
To apply the eyedrops, follow these steps:
o Wash your hands thoroughly with soap and water.
o Use a mirror or have someone else put the drops in your eye.
o Before using the eyedrops bottle for the first time, make sure the safety
strip on the front of the bottle is unbroken.
o Tear off the safety strip to break the seal.
o To open the bottle, unscrew the cap by turning as indicated by the arrows.
o Avoid touching the dropper against your eye or anything else.
o Lie down or tilt your head back.
o Holding the bottle between your thumb and index finger, place the dropper
as near as possible to your eyelid without touching it.
o Brace the remaining fingers of that hand against your cheek or nose.
o With the index finger of your other hand, pull the lower lid of the eye
down to form a pocket.
o Press lightly with the thumb or index finger over the Finger Push Area
until a single drop is dispensed into the pocket made by the lower lid and
the eye. Placing the drops on the surface of the eyeball can cause stinging.
o Close your eye and press lightly against the lower lid with your finger
for 2-3 minutes to keep the medication in the eye. Do not blink.
o Replace and tighten the cap right away. Do not wipe or rinse it off.
o Wipe off any excess liquid from your cheek with a clean tissue. Wash your
hands again.
O Special
precautions:
o Inform your doctor or pharmacist if you have
allergy to dorzolamide (Trusopt), timolol (Timoptic), sulfa drugs, or any
other medications.
o Inform your doctor and pharmacist what prescription and nonprescription
medications, vitamins, nutritional supplements, and herbal products you are
taking. Be sure to mention any of the following: beta blockers such as
atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol
XL), nadolol (Corgard), and propranolol (Inderal); calcium channel blockers
such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others),
felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene),
nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular),
and verapamil (Calan, Isoptin, Verelan); carbonic anhydrase inhibitors such
as acetazolamide (Diamox), dichlorphenamide (Danaride), and methazolamide (GlaucTabs,
Neptazane); clonidine (Catapres, Catapres-TTS); digoxin (Lanoxin); diuretics
('water pills'); quinidine (Quinidex); reserpine (Serpalan, Serpasil,
Serpatabs); and salicylate pain relievers such as aspirin, choline magnesium
trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid),
magnesium salicylate (Doan's, others), and salsalate (Argesic, Disalcid,
Salgesic). Your doctor may need to change the doses of your medications or
monitor you carefully for side effects.
o if you are using another topical eye medication, apply it at least 10
minutes before or after dorzolamide and timolol.
o inform your doctor if you are breast-feeding asthma, lung disease
(including chronic bronchitis and emphysema), heart disease, diabetes, an
overactive thyroid gland (hyperthyroidism), severe allergic reactions,
myasthenia gravis, and kidney or liver disease.
o Inform your doctor if you are pregnant, plan to become pregnant, or are
breast-feeding. If you become pregnant while using dorzolamide and timolol,
call your doctor.
o if you are having surgery, including dental surgery, tell the doctor or
dentist that you are using dorzolamide and timolol.
o you should know that dorzolamide and timolol solution contains
benzalkonium chloride, which can be absorbed by soft contact lenses. If you
wear contact lenses, remove them before applying dorzolamide and timolol and
put them back in 15 minutes later.
o if you have an eye injury, infection, or surgery while using dorzolamide
and timolol, ask your doctor if you should continue using the same eyedrops
container.
o you should know that if you have allergic reactions to different
substances, your reactions may be worse while you are using dorzolamide and
timolol, and your allergic reactions may not respond to the usual doses of
injectable epinephrine.
O
Possible Adverse
Effects:
Dorzolamide and timolol may cause adverse effects. Inform your doctor if any
of the following symptoms are severe or do not go away:
o taste changes (bitter, sour, or unusual taste)
o eye burning or stinging
o itchy eyes
o dry eyes
o eye tearing
o dizziness
Some adverse effects could be serious. The following symptoms are uncommon,
but if you experience any of them, call your doctor without delay:
o blurred vision (Impaired vision)
o skin rash
o swelling of the hands, feet, ankles, or lower legs
o shortness of breath
o pink eye
o redness or swelling of the eyelid
o muscle weakness
O Possible Symptoms
of Overdose:
o dizziness
o headache
o shortness of breath
o difficulty swallowing or breathing
o chest pain
o confusion
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