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Fluvastatin

O  General Information and Indications:

Fluvastatin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. Fluvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body. Accumulation of cholesterol and fats along the walls of the arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to the heart, brain, and other parts of the body. Lowering blood levels of cholesterol and fats may help to prevent heart disease, angina (chest pain), strokes, and heart attacks.

O  Information For Users:

Fluvastatin comes as a capsule and an extended-release (long-acting) tablet to take by mouth. The capsule is usually taken with or without food once a day at bedtime or twice a day. The extended-release tablet is usually taken once a day at bedtime with or without food. To help you remember to take fluvastatin, take it around the same time every day. Follow the directions on your prescription label, ask your doctor or pharmacist If you have any questions. Take fluvastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your health care provider.

Swallow the extended-release tablets whole; do not split, chew, or crush them.

Your doctor might start you on a low dose of fluvastatin and slowly increase your dose.

Continue taking fluvastatin even if you feel well. Do not discontinue taking fluvastatin without informing your doctor.
Other uses for this medicine

O  Special precautions:

o Inform your doctor or pharmacist if you have allergy to fluvastatin or any other medications.
o Inform your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin; cimetidine (Tagamet); diclofenac (Cataflam, Voltaren); glyburide (DiaBeta, Glynase, Micronase); ketoconazole (Nizoral); omeprazole (Prilosec); other cholesterol-lowering medications such as fenofibrate (Tricor) and gemfibrozil (Lopid); phenytoin (Dilantin); ranitidine (Zantac); rifampin (Rifadin, Rimactane); and spironolactone (Aldactone). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
o if you are taking cholestyramine (Questran), take it at least 2 hours before fluvastatin.
o Inform your doctor if you drink large amounts of alcohol and if you have or have ever had liver or kidney disease.
o Inform your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking fluvastatin, stop taking fluvastatin and call your doctor without delay. Fluvastatin may harm the fetus.
o if you are having surgery, including dental surgery, Inform your doctor or dentist that you are taking fluvastatin.
o if you have a severe infection, surgery, an injury, low blood pressure, or seizures while taking fluvastatin, talk to your doctor about stopping the medication for a while.

Eat a low-cholesterol, low-fat diet. This kind of diet includes cottage cheese, fat-free milk, fish (not canned in oil), vegetables, poultry, egg whites, and polyunsaturated oils and margarines (corn, safflower, canola, and soybean oils). Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, lard, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips, coconut, cheese (other than cottage cheese), coconut oil, palm oil, and fried foods.


O  Possible Adverse Effects:

Fluvastatin may cause adverse effects. Inform your doctor if any of the following symptoms are severe or do not go away:

o headache
o heartburn
o stomach pain
o upset stomach
o difficulty falling asleep or staying asleep
o sinus pain

Some adverse effects could be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor without delay:

o muscle pain, tenderness, or weakness
o lack of energy or fever
o yellowing of the skin or eyes, jaundice
o pain during urination
o urinary urgency and/or frequency

O  Brand Name(s):

o Lescol®
o Lescol® XL

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