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Non-steroidal anti-inflammatory drugs (NSAIDs)
How do NSAIDs Work?
The body produces substances called prostaglandins which play a role in causing inflammation and pain. NSAIDS work mainly by preventing the formation of prostaglandins which decreases the pain and inflammation.

Examples of NSAIDS
There are many different types of NSAIDS, including aspirin and other salicylates. Examples include; ibuprofen (Motrin, Advil), naproxen (Naprosyn), sulindac (Clinoril), diclofenac (Voltaren), piroxicam (Feldene), ketoprofen (Orudis), diflunisal (Dolobid), nabumetone (Relafen), etodolac (Lodine), oxaprozin (Daypro), indomethacin (Indocin).

Possible Side effects

These include upset stomach, headache, ringing in the ears, dizziness, rash, itching, easy bruising, fluid retention, blood in the stool.

Precautions
Since NSAIDs can cause stomach and intestinal upset and irritation, take them with food or after meals. You should also avoid alcoholic beverages, because alcohol can aggravate these stomach and intestinal problems.

Talk to your doctor about whether NSAIDs are right for you. For some people, the benefits outweigh the risks.
Do not take NSAIDs if you have ever had an allergic reaction to any type of pain medicine.
You should not take prescription NSAIDs if you have recently had heart bypass surgery.
Do not take more than the recommended dose.
Long-term use of NSAIDs may cause ulcers and high blood pressure.
Some patients taking NSAIDs become more sensitive to sunlight. Use sunblock and protective clothing; avoid exposure to sunlight.
You may use NSAIDs cautiously during pregnancy, but do not take them during the first 3 months of your pregnancy or just before delivery. NSAIDs appear in breast milk and should be used cautiously if you are breastfeeding.

Talk to your doctor before taking NSAIDs if you have:

  -Ulcers or a history of stomach or intestinal bleeding.
  -Stomach pain, upset stomach, or heartburn that lasts or comes back.
  -Anemia.
  -Bleeding problems.
  -A habit of drinking more than 3 alcoholic drinks a day. This increases your risk of stomach bleeding.
  -High blood pressure.
  -Kidney, liver, or heart disease.
  -Any serious health condition.

Talk to your doctor before using NSAIDs if you take:

  -Blood thinners (anticoagulants).
  -Diuretics (water pills).
  -Medicine for arthritis or diabetes.
  -ASA to protect your heart.
  -Lithium.
  -Any other drugs.

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