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Carvedilol

General Information and Indications:

Carvedilol is used in combination with other drugs to treat heart failure. It also is used alone or in combination with other medications to treat high blood pressure. Carvedilol is a combination of two classes of drugs called beta-blockers and alpha-blockers. It works by relaxing the blood vessels so your heart does not have to pump as hard.

Information For Users:

Carvedilol comes as a tablet to take by mouth. It is usually taken twice a day with food. You will start out taking a low dose of carvedilol, and your doctor will increase your dose every 1 to 2 weeks until you are taking a dose that works well for you. When you start carvedilol and whenever your doctor increases your dose you will be closely watched to make sure the dose is not too high for you. Follow the directions on your prescription label, ask your doctor or pharmacist If you have any questions. Take carvedilol exactly as directed. Do not take more or less of it or take it more often than prescribed by your health care provider.

Carvedilol controls high blood pressure and heart failure but does not cure them. Your blood pressure should lower within 30 minutes and your symptoms of heart failure should begin to improve within the first hour of beginning carvedilol. Continue taking carvedilol even if you feel well. Do not discontinue taking carvedilol without informing your doctor. Abruptly stopping carvedilol can worsen your symptoms. Your doctor will probably want to decrease your dose gradually over 1 to 2 weeks.
Other uses for this medicine

Carvedilol also is used occasionally to treat angina (chest pain) and heart muscle disease. Talk to your doctor about the possible risks of using this medication.

special precautions:

o Inform your doctor and pharmacist if you have a history of allergic reactions to any substance (for example, food products or bee stings) or are allergic to carvedilol or any other medications.
o Inform your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cimetidine (Tagamet), clonidine (Catapres), cyclosporine (Neoral, Sandimmune), digoxin (Lanoxicaps, Lanoxin), diltiazem (Cardizem, Cardizem C, Dilacor XR), fluoxetine (Prozac), insulin, oral medications for diabetes, paroxetine (Paxil), phenelzine (Nardil), propafenone (Rythmol), quinidine (Quinaglute, Dura-Tabs, others), reserpine (Serpalan, Serpasil), rifampin (Rifadin, Rifamate, Rifater, Rimactane), tranylcypromine (Parnate), verapamil (Calan, Covera-HS, Verelan), and vitamins and herbal products.
o inform your doctor if you are breast-feeding asthma or another lung disease; blood vessel disease; heart, kidney, or liver disease; diabetes; pheochromocytoma; or an overactive thyroid gland.
o Inform your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking carvedilol, call your doctor.
o if you are having surgery, including dental surgery, Inform your doctor or dentist that you are taking carvedilol.
o you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
o you should know that this drug may make you dizzy and lightheaded when you are standing. You should sit or lie down when these symptoms occur and then stand up slowly.


Possible Adverse Effects:

Side effects from carvedilol can occur. Inform your doctor if any of the following symptoms are severe or do not go away:

o tiredness
o lightheadedness
o dizziness
o body or leg swelling
o headache
o diarrhea
o vision changes
o joint pain
o difficulty falling or staying asleep

If you have any of the following symptoms, call your doctor without delay:

o fainting
o difficulty breathing
o weight gain
o chest pain
o slow, irregular heartbeat
o abdominal pain
o dark urine
o yellowing of the skin or eyes, jaundice
o loss of consciousness
o vomiting
o loss of appetite (anorexia)
o seizures
o changes in blood sugar level
o frequent urination
o thirst
o dry mouth
o flushing
o dry skin
o sore throat, fever, cough, or other signs of infection

Brand Name(s):

o Coreg®
o Coreg® Tiltabs®

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