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Doxazosine

General Information and Indications:

Doxazosin is used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), which include difficulty in urination (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency. It is also used alone or in combination with other medications to treat high blood pressure. Doxazosin is in a class of medications called alpha-blockers. It relieves the symptoms of BPH by relaxing the muscles of the bladder and prostate. It lowers blood pressure by relaxing the blood vessels so that blood can flow more easily through the body.

Information For Users:

Doxazosin comes as a tablet to take by mouth. It is usually taken with or without food once a day in the morning or in the evening. To help you remember to take doxazosin, take it around the same time every day. Follow the directions on your prescription label, ask your doctor or pharmacist If you have any questions. Take doxazosin exactly as directed. Do not take more or less of it or take it more often than prescribed by your health care provider.

Your doctor will start you on a low dose of doxazosin and slowly increase your dose, not more than once every 1 to 2 weeks. If you stop taking doxazosin for a few days or longer, your doctor will have to start you again on the lowest dose and slowly increase your dose.

Doxazosin controls high blood pressure and the symptoms of BPH but does not cure them. Continue taking doxazosin even if you feel well. Do not discontinue taking doxazosin without informing your doctor.
Other uses for this medicine

Doxazosin also is used sometimes with other medications to treat congestive heart failure. Talk to your doctor about the possible risks of using this medication for your condition.

Special precautions:

o Inform your doctor or pharmacist if you have allergy to doxazosin, prazosin (Minipress), terazosin (Hytrin), or any other medications.
o Inform your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: other medications for high blood pressure. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
o inform your doctor if you are breast-feeding liver disease.
o Inform your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking doxazosin, call your doctor.
o if you are having surgery, including dental surgery, Inform your doctor or dentist that you are taking doxazosin.
o you should know that doxazosin may make you drowsy or dizzy. Do not drive a car or operate machinery for 24 hours after the first time you take doxazosin or after your dose is increased.
o you should know that doxazosin may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking doxazosin and when your dose is increased. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. If you experience these symptoms, sit or lie down.

Your doctor may prescribe a low-salt or low-sodium diet. Follow these directions carefully.


Possible Adverse Effects:

Doxazosin may cause adverse effects. Inform your doctor if any of the following symptoms are severe or do not go away:

o dizziness
o lightheadedness
o extreme tiredness (fatigue)
o swelling of the hands, feet, ankles, or lower legs
o shortness of breath
o dry mouth
o drowsiness
o muscle or joint pain or weakness
o abnormal vision
o runny nose
o decreased sexual ability (Impotence)

Some adverse effects could be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor without delay:

o rapid, pounding, or irregular heartbeat
o fainting
o painful erection of the penis that lasts for hours

Possible Symptoms of Overdose:

o dizziness
o lightheadedness
o fainting
o seizure

Brand Name(s):

o Cardura®


 

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