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Nifedipine

General Information and Indications:

Nifedipine is used to treat high blood pressure. It relaxes your blood vessels so your heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart to control chest pain (angina). If taken regularly, nifedipine controls chest pain, but it does not stop chest pain once it starts. Your doctor may give you a different medication to take when you have chest pain.

Information For Users:

Nifedipine comes as a capsule and an extended-release tablet (long-acting) to take by mouth. It is usually taken one or three times a day. The extended-release tablet should be taken on an empty stomach, either 1 hour before or 2 hours after a meal, and should be swallowed whole. Do not chew, divide, or crush the tablet. Follow the directions on your prescription label, ask your doctor or pharmacist If you have any questions. Take nifedipine exactly as directed. Do not take more or less of it or take it more often than prescribed by your health care provider.

Nifedipine controls high blood pressure and chest pain (angina) but does not cure them. Continue taking nifedipine even if you feel well. Do not discontinue taking nifedipine without informing your doctor.
Other uses for this medicine

Nifedipine is also used sometimes to treat migraine headaches, Raynaud's syndrome, congestive heart failure, and cardiomyopathy. Talk to your doctor about the possible risks of using this medication.

Special precautions:

o Inform your doctor or pharmacist if you have allergy to nifedipine or any other medications.
o Inform your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cimetidine (Tagamet); fentanyl (Duragesic); heart and blood pressure medications like beta-blockers, digoxin (Lanoxin), warfarin (Coumadin), and quinidine (Quinaglute, Quinidex); phenytoin (Dilantin); ranitidine (Zantac); and vitamins.
o inform your doctor if you are breast-feeding heart, liver, or kidney disease.
o Inform your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking nifedipine, call your doctor.
o if you are having surgery, including dental surgery, Inform your doctor or dentist that you are taking nifedipine.

Nifedipine capsules may be taken with or without food, but the nifedipine extended-release tablets should be taken on an empty stomach, either 1 hour before or 2 hours after a meal.

Avoid drinking grapefruit juice or eating grapefruit 1 hour before or for 2 hours after taking nifedipine.

Do not drink alcoholic beverages while taking this medication.

Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.


Possible Adverse Effects:

Though adverse effects of nifedipine are not common, they could occur. Inform your doctor if any of the following symptoms are severe or do not go away:

o headache
o upset stomach
o lightheadedness or dizziness
o extreme tiredness (fatigue)
o flushing
o heartburn
o fast heartbeat
o muscle cramps
o enlargement of gum tissue around teeth
o constipation
o nasal congestion
o cough
o decreased sexual ability (Impotence)

If you have any of the following symptoms, call your doctor without delay:

o swelling of the face, eyes, lips, tongue, arms, or legs
o difficulty swallowing or breathing
o fainting
o rash
o yellowing of the skin or eyes, jaundice
o increase in frequency or severity of chest pain (angina)

Brand Name(s):

o Adalat®
o Adalat® CC
o Nifedical® XL
o Procardia XL®

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