General
Information and Indications:
Glyburide is used to treat type 2 (noninsulin-dependent) diabetes (formerly
'adult-onset'), particularly in people whose diabetes cannot be controlled
by diet alone. Glyburide lowers blood sugar by stimulating the pancreas to
secrete insulin and helping the body use insulin efficiently. The pancreas
must produce insulin for this medication to work. Glyburide is not used to
treat type 1 (insulin-dependent) diabetes (formerly 'juvenile-onset').
Information
For Users:
Glyburide comes in tablets to take by mouth. It is
usually taken once a day with breakfast or twice a day (when a large daily
dose is required). Follow the directions on your prescription label, ask
your doctor or pharmacist If you have any questions. Take glyburide exactly
as directed. Do not take more or less of it or take it more often than
prescribed by your health care provider.
special
precautions:
o Inform your doctor or pharmacist if you have
allergy to glyburide or any other medications.
o Inform your doctor and pharmacist what prescription and nonprescription
medications you are taking, especially antibiotics, anticoagulants ('blood
thinners') such as warfarin (Coumadin), dexamethasone (Decadron), diuretics
('water pills'), estrogens, isoniazid (INH), MAO inhibitors [phenelzine (Nardil)
and tranylcypromine (Parnate)], medications for high blood pressure or heart
disease, metformin (Glucophage), niacin (nicotinic acid), oral
contraceptives, phenytoin (Dilantin), prednisone, probenecid (Benemid), and
vitamins.
o inform your doctor if you are breast-feeding heart or kidney disease.
o Inform your doctor if you are pregnant, plan to become pregnant, or are
breast-feeding. If you become pregnant while taking glyburide, call your
doctor.
o if you are having surgery, including dental surgery, Inform your doctor or
dentist that you are taking glyburide.
o you should know that this drug may make you drowsy. Do not drive a car or
operate machinery until you know how this drug affects you.
o remember that alcohol can add to the drowsiness caused by this drug.
o Inform your doctor if you use tobacco products. Cigarette smoking may
decrease the effectiveness of glyburide.
o plan to avoid unnecessary or prolonged exposure to sunlight and to wear
protective clothing, sunglasses, and sunscreen. Glyburide may make your skin
sensitive to sunlight.
Be sure to follow all exercise and dietary recommendations made by your
doctor or dietitian. It is important to eat a healthful diet.
Possible Adverse Effects:
You should know the symptoms of low and high
blood sugar and what to do if you have them.
Eat or drink a food or beverage with sugar in it, such as hard candy or
fruit juice, and call your doctor without delay if you have any of the
symptoms of hypoglycemia (low blood sugar) :
o shakiness
o lightheadedness or dizziness
o sweating
o confusion
o nervousness or irritability
o sudden changes in behavior or mood
o headache
o numbness or tingling around the mouth
o weakness
o pale skin
o sudden hunger
o clumsy or jerky movements
o seizures
call your doctor without delay if you have any of the following symptoms of
hyperglycemia (high blood sugar):
o extreme thirst
o frequent urination
o extreme hunger
o weakness
o blurred vision (Impaired vision)
If high blood sugar is not treated, a serious, life-threatening condition
called diabetic ketoacidosis could develop. call your doctor without delay
if you have any of the these symptoms:
o dry mouth
o upset stomach and vomiting
o shortness of breath
o breath that smells fruity
o decreased consciousness
Glyburide may cause adverse effects. If you have any of the following
symptoms, call your doctor without delay:
o skin rash
o itching or redness
o exaggerated sunburn
o yellowing of the skin or eyes, jaundice
o light-colored stools
o dark urine
o unusual bruising or bleeding
o fever
o sore throat
Brand Name(s):
o Diabeta®
o Glynase®
o Micronase® |
